Rowe & Wren
← Thyroid guide

Still not feeling right?

Film 5 of 5 · 1 min 16 · No sound needed

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The film in words

Some people on levothyroxine still have symptoms even when their TSH is in range. Taking the medicine and having regular blood tests may not be enough on their own to feel well all of the time.

It’s common to feel emotionally and mentally “not quite right” for some time, even after blood tests return to normal.

Levothyroxine is slow-acting: it may take several months for symptoms to ease, and a little while after a dose change.

How it’s taken matters. Food, drinks with caffeine, and some medicines and supplements can affect how well it’s absorbed.

If you’re doing those things and still don’t feel well, the British Thyroid Foundation’s advice is to make an appointment with your doctor to talk about your symptoms.

Your doctor may look for other causes, such as low iron, low vitamin B12, low vitamin D and coeliac disease. If these have been ruled out, you can ask your GP to consider referring you to a thyroid specialist.

On levothyroxine, if symptoms carry on, guidance for doctors is to consider testing free T4 as well as TSH.

You can ask your doctor whether there’s room for a slight adjustment of your dose, if your TSH can be kept within the range. Don’t change your dose without talking to your doctor first.

Noting how you feel each month, beside your results, gives you something clear to take to an appointment. Check in, and print the summary for your GP.

Sources: British Thyroid Foundation: hypothyroidism; British Thyroid Foundation: living with hypothyroidism; NICE NG145; British Thyroid Foundation: thyroid function tests

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General information, not a diagnosis. Your GP can tell you what your results mean for you.